GMP-Compliant Sieving & Blending for API Manufacturing – Powered by JS Vibro
In API (Active Pharmaceutical Ingredient) production, precision, hygiene, and batch uniformity are non-negotiable. Materials like fine drug powders, excipients, and intermediates require gentle yet efficient handling to maintain their chemical stability and bioavailability.
A pharmaceutical manufacturer approached JS Vibro to address challenges in sieving micronized powders and blending delicate compounds while maintaining strict GMP protocols.
Purpose-Built Systems for API Manufacturing
Vibro Sifter (Pharma-Grade) was deployed to eliminate foreign particles, lumps, and cross-contaminants from APIs like paracetamol, ibuprofen, and excipients—ensuring fine particle screening in compliance with FDA and GMP standards.
Ribbon Blender (Hygienic Design) was used to achieve consistent, gentle mixing of APIs with excipients like lactose, microcrystalline cellulose, and starch—delivering uniform blend density without thermal degradation or dust generation.
Distinct Advantages of JS Vibro for Pharmaceutical APIs:
- GMP-Compliant Design: Mirror-polished contact parts, crevice-free finish, and sanitary seals
- HEPA Filter & Dust-Free Operation: Ensures cleanroom compatibility
- Precise Sieving: Up to 500 mesh for ultra-fine powders
- Tool-Free Cleaning: Quick disassembly for batch changeover
- Gentle Blending: Preserves particle integrity and flow properties
Perfect For:
- API screening before tablet or capsule formulation
- Powder blending for direct compression
- Intermediate bulk mixing in pharma R&D
- Controlled mixing of excipients and active blends
